There's many cities on the map that, in reality, are practically invisible. They have a much lower stature among American cities than their size would suggest, almost to the point where they're forgotten. They almost never make the news, they have no iconic institutions, and many people in the country might not even know that the place actually exists. There are places where a fugitive might run to, because nobody would even think of looking for someone there.
A few that come to mind:
Wichita Falls, Texas. Among the fourth-tier Texas cities of Abeline, Waco, Tyler, College Station, and Beaumont, Wichita Falls is ... well, I don't know. The entire time I lived in Austin, I never heard the place mentioned once.
Farmington, New Mexico. It's one of the largest cities in the state, behind Albuquerque, Las Cruces and Santa Fe, but even New Mexicans seem unaware of its existence. It's tucked away in the far northwestern part of the state, hours away from the Interstate system and any cities of a similar or larger size.
Medford, Oregon. I don't know what else to say about it. When you think about cities in Oregon, lots of places come to mind: Portland, Bend, Salem, Eugene, and Corvallis. Medford is larger than many of the places I just mentioned, but I never think of it when thinking of Oregon. I've never heard anyone else mention it, either.