In my travels throughout the US, I've noticed that certain types of businesses are called a completely unique name in one city or region. If you refer to that type of business using the local vernacular outside the region, most people will have no idea what you're talking about. A few examples:
Banquet hall: in Rochester, it's a party house, while in Cleveland it's called a party center. When I think of "party house", I don't think of huge Italian weddings, but rather this:
Inner city convenience store: NYC has bodegas, and Detroit has party stores.
Convenience store: in some parts of southern Ontario near the US border, many are called a milk bar.
Can you think of any other examples?