All of the four largest cities in California grew over the past ten years, each representing their largest population ever. To quote the census release:
Data for California show that the five most populous incorporated places and their 2010 Census counts are Los Angeles, 3,792,621; San Diego, 1,307,402; San Jose, 945,942; San Francisco, 805,235; and Fresno, 494,665. Los Angeles grew by 2.6 percent since the 2000 Census. San Diego grew by 6.9 percent, San Jose grew by 5.7 percent, San Francisco grew by 3.7 percent, and Fresno grew by 15.7 percent.