I used to think those were bad until I started getting tons of disturbing e-mails about "girls on the farm." Now they should be threatened.
I can barely leave my cell phone on anymore because I get lots of pre-recorded telemarketer calls. I'll also get lots of mysterious calls for a "Raphael." Hopefully I don't have some druglord's cell phone number.
I never publish a personal e-mail address in a location where the spambots can grep it. For Web sites requiring an e-mail address for registration, I create a new address specifically for e-mail from that site. I tell friends to NEVER send me Internet post cards, "forward this page to a friend" type links, or enter my e-mail address into a Web form unless it's Web-based e-mail that they use.
Even without filters, my spam count is almost zero.
My work email address is on my business card -- anybody gets honked off with me -- which never happens, me being a public official and all ;-) -- and they can just load me up with spam. Our ISP has a pretty good blocker, but they are always emailing me to check what they've quarantined as "suspicious mail". I usually just hit "delete all" and go on about my business.